Free Shipping On All Orders Over CAD $99

EstroVantage EM® Estrogen Modulator 90 Vegetarian Capsules

EstroVantage EM® Estrogen Modulator 90 Vegetarian Capsules

Regular price
Sale price
Quantity must be 1 or more


  • Offers a full array of protective compounds from cruciferous vegetables, including I3C, DIM, and sulforaphane
  • Provides a unique blend of botanicals that improve estrogen metabolism, shifting away from carcinogenic metabolites
  • Supports detoxification of a variety of environmental toxins as well as naturally produced hormones by enhancing phase 1 and phase 2 liver enzymes
  • Contains botanicals with potent anti-inflammatory activity 
  • Suitable for vegetarians/vegans 

Feature Summary

EstroVantage EM provides a comprehensive formula of plant-based compounds that improve the metabolism of estrogen and its metabolites. Cruciferous vegetables contain a variety of glucosinolates, which some studies have associated with a reduction in cancer incidence when consumed in greater amounts, most likely by causing a shift in metabolism to less carcinogenic estrogen metabolites.1,2 EstroVantage EM contains indole-3-carbinol (I3C) and its metabolite 3,3’-diindolylmethane (DIM), as well as sulforaphane from broccoli powder, all of which have been linked to lower rates of neoplastic changes and a more favourable estrogen profile.3-6 Not only do these glucosinolates improve estrogen metabolism, they also reduce inflammation by targeting key signalling molecules, such as Nrf2 and NF-κB.7,8 

EstroVantage EM also includes other potent plant compounds that reduce inflammation and block carcinogenic pathways. Silymarin, a milk thistle extract, down-regulates gene products involved in the proliferation of tumour cells, along with their invasion, angiogenesis, and metastasis. In addition, it enhances glucuronidation and maintains glutathione levels.9-11 This unique combination provides green tea polyphenols, lycopene (tomato extract), turmeric and rosemary extracts, as well as calcium D-glucarate, all of which have been shown to favourably shift estrogen metabolism and reduce carcinogenic risk.12-14

Medicinal Ingredients

Each Vegetarian Capsule Contains:
Calcium D-Glucarate (d-Glucaric Acid Calcium Salt) 75 mg
Indole-3-Carbinol (3-Hydroxymethylindole) 75 mg
Green Tea Extract (Camellia sinensis) (leaf) (80% Catechins, 45% EGCG*, <1% Caffeine) 50 mg
Tomato Extract (Lycopersicon esculentum) (fruit) (5% Lycopene) 50 mg
Broccoli Powder (Brassica oleracea var. italica) (aerial) (0.36% Sulforaphane) 27.5 mg
DIM (3,3’-Diindolylmethane) 25 mg
Turmeric Extract (Curcuma longa) (rhizome) (95% Curcuminoids) 25 mg
Milk Thistle Extract (Silybum marianum) (seed) (50–60% Silymarin) 25 mg
Rosemary 6:1 Extract (Rosmarinus officinalis) (leaf) 12.5 mg
* Epigallocatechin-3-gallate

Non-Medicinal Ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.


3 capsules once per day with food or as directed by a health care practitioner. Consult a health care practitioner for use beyond 12 weeks.


Contains no artificial colours, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.